Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia

There is conflicting information about the influence of body mass index (BMI) on the pharmacokinetics, toxicity, and outcome of chemotherapy. We compared pharmacokinetics, outcome, and toxicity data across 4 BMI groups (underweight, BMI ≤ 10th percentile; normal; at risk of overweight, BMI ≥ 85th an...

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Main Authors: Hijiya, Nobuko, Panetta, John C., Zhou, Yinmei, Kyzer, Emily P., Howard, Scott C., Jeha, Sima, Razzouk, Bassem I., Ribeiro, Raul C., Rubnitz, Jeffrey E., Hudson, Melissa M., Sandlund, John T., Pui, Ching-Hon, Relling, Mary V.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Hematology 2006
Teme:
Clinical Trials and Observations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895448/
https://ncbi.nlm.nih.gov/pubmed/16917005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-024414
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