Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia

There is conflicting information about the influence of body mass index (BMI) on the pharmacokinetics, toxicity, and outcome of chemotherapy. We compared pharmacokinetics, outcome, and toxicity data across 4 BMI groups (underweight, BMI ≤ 10th percentile; normal; at risk of overweight, BMI ≥ 85th an...

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Bibliographic Details
Main Authors: Hijiya, Nobuko, Panetta, John C., Zhou, Yinmei, Kyzer, Emily P., Howard, Scott C., Jeha, Sima, Razzouk, Bassem I., Ribeiro, Raul C., Rubnitz, Jeffrey E., Hudson, Melissa M., Sandlund, John T., Pui, Ching-Hon, Relling, Mary V.
Format: Artigo
Language:Inglês
Published: The American Society of Hematology 2006
Subjects:
Clinical Trials and Observations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895448/
https://ncbi.nlm.nih.gov/pubmed/16917005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-05-024414
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