T-bet concomitantly controls migration, survival, and effector functions during the development of Vα14i NKT cells

Vα14i natural killer T (NKT)–cell function has been implicated in a number of disease conditions. The molecular events that drive Vα14i NKT-cell development remain elusive. We recently showed that T-bet is required for the terminal maturation of these cells. Here we identify some of the genetic targ...

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Autori principali: Matsuda, Jennifer L., Zhang, Qianjun, Ndonye, Rachel, Richardson, Stewart K., Howell, Amy R., Gapin, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2006
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895373/
https://ncbi.nlm.nih.gov/pubmed/16357323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-08-3103
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