Differentiation of naive cord-blood T cells into CD19-specific cytolytic effectors for posttransplantation adoptive immunotherapy

Disease relapse is a barrier to achieving therapeutic success after unrelated umbilical cord-blood transplantation (UCBT) for B-lineage acute lymphoblastic leukemia (B-ALL). While adoptive transfer of donor-derived tumor-specific T cells is a conceptually attractive approach to eliminating residual...

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Bibliographische Detailangaben
Hauptverfasser: Serrano, Lisa Marie, Pfeiffer, Timothy, Olivares, Simon, Numbenjapon, Tontanai, Bennitt, Jennifer, Kim, Daniel, Smith, David, McNamara, George, Al-Kadhimi, Zaid, Rosenthal, Joseph, Forman, Stephen J., Jensen, Michael C., Cooper, Laurence J. N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Gene Therapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895371/
https://ncbi.nlm.nih.gov/pubmed/16352804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3904
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