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Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis

To produce blood platelets, megakaryocytes elaborate proplatelets, accompanied by expansion of membrane surface area and dramatic cytoskeletal rearrangements. The invaginated demarcation membrane system (DMS), a hallmark of mature cells, has been proposed as the source of proplatelet membranes. By d...

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Main Authors: Schulze, Harald, Korpal, Manav, Hurov, Jonathan, Kim, Sang-We, Zhang, Jinghang, Cantley, Lewis C., Graf, Thomas, Shivdasani, Ramesh A.
格式: Artigo
語言:Inglês
出版: The American Society of Hematology 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895279/
https://ncbi.nlm.nih.gov/pubmed/16434494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2755
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