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Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis

To produce blood platelets, megakaryocytes elaborate proplatelets, accompanied by expansion of membrane surface area and dramatic cytoskeletal rearrangements. The invaginated demarcation membrane system (DMS), a hallmark of mature cells, has been proposed as the source of proplatelet membranes. By d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schulze, Harald, Korpal, Manav, Hurov, Jonathan, Kim, Sang-We, Zhang, Jinghang, Cantley, Lewis C., Graf, Thomas, Shivdasani, Ramesh A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895279/
https://ncbi.nlm.nih.gov/pubmed/16434494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2755
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