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Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis

To produce blood platelets, megakaryocytes elaborate proplatelets, accompanied by expansion of membrane surface area and dramatic cytoskeletal rearrangements. The invaginated demarcation membrane system (DMS), a hallmark of mature cells, has been proposed as the source of proplatelet membranes. By d...

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Bibliographic Details
Main Authors: Schulze, Harald, Korpal, Manav, Hurov, Jonathan, Kim, Sang-We, Zhang, Jinghang, Cantley, Lewis C., Graf, Thomas, Shivdasani, Ramesh A.
Format: Artigo
Language:Inglês
Published: The American Society of Hematology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895279/
https://ncbi.nlm.nih.gov/pubmed/16434494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2755
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