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Replication of avian leukosis viruses with mutations at the primer binding site: use of alternative tRNAs as primers.

We have tested whether avian leukosis viruses (ALVs) can use tRNAs other than tRNATrp to initiate reverse transcription. The primer binding site (PBS) of a wild-type ALV provirus, which is complementary to the 3' end of tRNA(Trp), was replaced with sequences homologous to the 3' ends of si...

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Main Authors: Whitcomb, J M, Ortiz-Conde, B A, Hughes, S H
格式: Artigo
語言:Inglês
出版: 1995
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC189520/
https://ncbi.nlm.nih.gov/pubmed/7545245
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