Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs

Hepcidin is the principal iron regulatory hormone and its overproduction contributes to anemia of inflammation (AI). In vitro, hepcidin binds to and induces the degradation of the exclusive iron exporter ferroportin. We explored the effects and distribution of synthetic hepcidin in the mouse. A sing...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rivera, Seth, Nemeth, Elizabeta, Gabayan, Victoria, Lopez, Miguel A., Farshidi, Dina, Ganz, Tomas
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2005
Fag:
Red Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895137/
https://ncbi.nlm.nih.gov/pubmed/15933050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1766
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker