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Telomere loss, senescence, and genetic instability in CD4(+) T lymphocytes overexpressing hTERT
Little is known about the long-term consequences of overexpression of the human telomerase reverse transcriptase (hTERT) gene in T lymphocytes. To address this issue, we transduced polyclonal as well as clonally derived populations of naive and memory CD4(+) T cells from 2 healthy donors (aged 24 an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society of Hematology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895130/ https://ncbi.nlm.nih.gov/pubmed/15741219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-10-4144 |
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