Intrabodies targeting the Kaposi sarcoma–associated herpesvirus latency antigen inhibit viral persistence in lymphoma cells

Kaposi sarcoma–associated herpesvirus (KSHV) latency-associated nuclear antigen-1 (LANA1) is essential for the maintenance and segregation of viral episomes in KSHV latently infected B cells. We report development of intracellular, rabbit-derived antibodies generated by phage display technology, whi...

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Detalhes bibliográficos
Main Authors: Corte-Real, Sofia, Collins, Chris, da Silva, Frederico Aires, Simas, J. Pedro, Barbas, Carlos F., Chang, Yuan, Moore, Patrick, Goncalves, Joao
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895103/
https://ncbi.nlm.nih.gov/pubmed/16091453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1627
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