Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus Latency

Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus that infects humans and exhibits a biphasic life cycle consisting of latent and lytic phases. Following entry into host cells, the KSHV genome undergoes circularization and chromatinization into an extrachromosomal episome...

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Autores principales: Mel Campbell, Wan-Shan Yang, Wayne W. Yeh, Chen-Hsuan Kao, Pei-Ching Chang
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020-05-01
Colección:Frontiers in Microbiology
Materias:
Kaposi’s sarcoma-associated herpesvirus (KSHV)
epigenetic
DNA methylation
histone modification
post-translational modification (PTM)
long non-coding RNAs (lncRNAs)
Acceso en línea:https://www.frontiersin.org/article/10.3389/fmicb.2020.00850/full
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