NF-κB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)

Tumor necrosis factor (TNF)-α, a potent stimulus of nuclear factor-κB (NF-κB), is up-regulated in myelodysplastic syndrome (MDS). Here, we show that bone marrow mononuclear cells (BMMCs) and purified CD34(+) cells from patients with low-grade/early-stage MDS (refractory anemia/refractory anemia with...

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Autori principali: Kerbauy, Daniella M. B., Lesnikov, Vladimir, Abbasi, Nissa, Seal, Sudeshna, Scott, Bart, Deeg, H. Joachim
Natura: Artigo
Lingua:Inglês
Pubblicazione: © 2005 by The American Society of Hematology 2005
Soggetti:
Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895102/
https://ncbi.nlm.nih.gov/pubmed/16105982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-04-1424
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