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Differential responses of FLIP(long) and FLIP(short) overexpressing human myeloid leukemia cells to TNFα and TRAIL-initiated apoptotic signals

OBJECTIVE: Clonal marrow cells from patients with early myelodysplastic syndrome (MDS) undergo apoptosis in response to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL). Cells from advanced MDS are resistant to TRAIL. Two isoforms of the Flice inhibitory protein, FLIP(short(S))...

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Main Authors: Seal, Sudeshna, Hockenbery, David M., Spaulding, Emily, Kiem, Hans-Peter, Abbassi, Nissa, Deeg, H. Joachim
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645417/
https://ncbi.nlm.nih.gov/pubmed/18838202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.07.012
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