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Differential responses of FLIP(long) and FLIP(short) overexpressing human myeloid leukemia cells to TNFα and TRAIL-initiated apoptotic signals
OBJECTIVE: Clonal marrow cells from patients with early myelodysplastic syndrome (MDS) undergo apoptosis in response to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL). Cells from advanced MDS are resistant to TRAIL. Two isoforms of the Flice inhibitory protein, FLIP(short(S))...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645417/ https://ncbi.nlm.nih.gov/pubmed/18838202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.07.012 |
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