NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses

The presence of a metaphase cytogenetic abnormality (CA) is the key negative predictor of outcome in patients with multiple myeloma (MM). Gene expression profiling (GEP) of such patients showed increased expression of NY-ESO-1 compared to patients with normal cytogenetics (60% versus 31%; P = .004)....

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Autori principali: van Rhee, Frits, Szmania, Susann M., Zhan, Fenghuang, Gupta, Sushil K., Pomtree, Mindy, Lin, Pei, Batchu, Ramesh B., Moreno, Amberly, Spagnoli, Guilio, Shaughnessy, John, Tricot, Guido
Natura: Artigo
Lingua:Inglês
Pubblicazione: © 2005 by The American Society of Hematology 2005
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895070/
https://ncbi.nlm.nih.gov/pubmed/15671442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3707
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