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Identification of a human B-cell/myeloid common progenitor by the absence of CXCR4

CXCR4 is a chemokine receptor required for hematopoietic stem cell engraftment and B-cell development. This study found that a small fraction of primitive CD34(+)/CD19(+) B-cell progenitors do not express CXCR4. These CD34(+)/CD19(+)/CXCR4(-) cells were also remarkable for the relative lack of primi...

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Detalhes bibliográficos
Main Authors: Hou, Yong-Hao, Srour, Edward F., Ramsey, Heather, Dahl, Richard, Broxmeyer, Hal E., Hromas, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895023/
https://ncbi.nlm.nih.gov/pubmed/15650059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-07-2839
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