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Human immunodeficiency virus type 1 can use different tRNAs as primers for reverse transcription but selectively maintains a primer binding site complementary to tRNA(3Lys).

The initiation of human immunodeficiency virus type 1 (HIV-1) reverse transcription occurs at a site in the viral RNA genome which is designated the primer-binding site (PBS). The HIV-1 PBS is an 18-nucleotide sequence that is complementary to the 3'-terminal 18 nucleotides of tRNA(3Lys), which is u...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Wakefield, J K, Wolf, A G, Morrow, C D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189498/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7545240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.10.6021-6029.1995
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