Nucleotide substitutions within U5 are critical for efficient reverse transcription of human immunodeficiency virus type 1 with a primer binding site complementary to tRNA(His).

Sequence analysis of integrated proviruses of human immunodeficiency virus type 1 (HIV-1) which utilize tRNA(His) to initiate reverse transcription [virus derived from pHXB2(His-AC-TGT)] revealed five additional nucleotide substitutions in the U5 and primer binding site (PBS) regions (ATGAC for CCTG...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Li, Y, Zhang, Z, Wakefield, J K, Kang, S M, Morrow, C D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6315-6322.1997
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