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Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways

The human exosome is a 3′–5′ exoribonuclease complex that functions both in the nucleus and in the cytoplasm to either degrade or process RNA. Little is known yet about potential differences among core exosome complexes in these different cellular compartments and the roles of the individual subunit...

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Autores principales: van Dijk, Erwin L., Schilders, Geurt, Pruijn, Ger J.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894934/
https://ncbi.nlm.nih.gov/pubmed/17545563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.575107
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