Synergistic Effect of IGF-1 and OP-1 on Matrix Formation by Normal and OA Chondrocytes Cultured in Alginate Beads.

OBJECTIVE: Growth factor therapy may be useful for stimulation of cartilage matrix synthesis and repair. Thus, the purpose of our study was to further understand the effect of combined insulin-like growth factor 1 (IGF-1) and osteogenic protein 1 (OP-1) treatment on the matrix synthesized by human a...

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Main Authors: Chubinskaya, Susan, Hakimiyan, Arnavaz, Pacione, Carol, Yanke, Adam, Rappoport, Lev, Aigner, Thomas, Rueger, David C., Loeser, Richard F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894688/
https://ncbi.nlm.nih.gov/pubmed/17126570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2006.10.004
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