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Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr.

We investigated the fate of human immunodeficiency virus type 1 (HIV-1) viral DNA in infected peripheral blood lymphocytes and immortalized T-cell lines by using a replication-defective HIV-1. We observed that integrated HIV-1 DNA and viral gene expression decrease over time. A frameshift mutation i...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Planelles, V, Bachelerie, F, Jowett, J B, Haislip, A, Xie, Y, Banooni, P, Masuda, T, Chen, I S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7637036/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5883-5889.1995
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