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Loss-of-Function Alleles of the JIL-1 Histone H3S10 Kinase Enhance Position-Effect Variegation at Pericentric Sites in Drosophila Heterochromatin

In this study we show that loss-of-function alleles of the JIL-1 histone H3S10 kinase act as enhancers of position-effect variegation at pericentric sites whereas the gain-of-function JIL-1(Su(var)3-1[3]) allele acts as a suppressor strongly supporting a functional role for JIL-1 in maintaining euch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bao, Xiaomin, Deng, Huai, Johansen, Jørgen, Girton, Jack, Johansen, Kristen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894597/
https://ncbi.nlm.nih.gov/pubmed/17435241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.073676
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