Loss-Of-Function Alleles of the JIL-1 Kinase Are Strong Suppressors of Position Effect Variegation of the w(m4) Allele in Drosophila

In this article we show that hypomorphic loss-of-function alleles of the JIL-1 histone H3S10 kinase are strong suppressors of position effect variegation (PEV) of the w(m4) allele and that lack of JIL-1 activity can counteract the effect of the dominant enhancer E(var)2-1 on PEV.

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Hlavní autoři: Lerach, Stephanie, Zhang, Weiguo, Bao, Xiaomin, Deng, Huai, Girton, Jack, Johansen, Jørgen, Johansen, Kristen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright © 2006 by the Genetics Society of America 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569694/
https://ncbi.nlm.nih.gov/pubmed/16702418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.059253
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