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The lipid A biosynthesis mutation lpxA2 of Escherichia coli results in drastic antibiotic supersusceptibility.

The conditionally lethal lpxA2 mutant of Escherichia coli, which lacks detectable UDP-N-acetylglucosamine acyltransferase activity and which produces greatly reduced amounts of lipid A after a shift to 42 degrees C (S. Galloway and C. R. H. Raetz, J. Biol. Chem. 265:6394-6402, 1990), was found to be...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Vuorio, R, Vaara, M
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189438/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1503445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.4.826
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