Structure-Based Virtual Screening of <i>Pseudomonas aeruginosa</i> LpxA Inhibitors using Pharmacophore-Based Approach
Multidrug resistance in <i>Pseudomonas aeruginosa</i> is a noticeable and ongoing major obstacle for inhibitor design. In <i>P. aeruginosa,</i> uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) acetyltransferase (PaLpxA) is an essential enzyme of lipid A biosynthesis and an attractive drug target...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2020-02-01
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| coleção: | Biomolecules |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2218-273X/10/2/266 |
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