Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine.

3'-Fluoro-3'-deoxythymidine (FLT), a candidate anti-AIDS compound in clinical trials, showed anti-human immunodeficiency virus type 1 (HIV-1) potency (50% effective concentration, 0.0052 microM) slightly better than or equal to that of 3'-azido-3'-deoxythymidine (AZT) in MT4 cells and was threefold...

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出版年:	Antimicrob Agents Chemother
主要な著者:	Kong, X B, Zhu, Q Y, Vidal, P M, Watanabe, K A, Polsky, B, Armstrong, D, Ostrander, M, Lang, S A, Muchmore, E, Chou, T C
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1992
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1503443/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.4.808
タグ:	タグ追加タグなし, このレコードへの初めてのタグを付けませんか!

Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine.

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