Mapping of mutations contributing to the temperature sensitivity of the Sabin 1 vaccine strain of poliovirus.
The temperature-sensitive and attenuated phenotypes of the Sabin type 1 vaccine strain of poliovirus result from numerous point mutations which occurred in the virulent Mahoney virus parent. One of these mutations is located in a 3D polymerase (3Dpol) codon (U-6203-->C, Tyr-73-->His) and is involved...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
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| المؤلفون الرئيسيون: | , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1995
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189363/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7636970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5278-5286.1995 |
| الوسوم: |
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