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Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase.

The interferon-inducible, RNA-dependent protein kinase (PKR) is activated by autophosphorylation, a process mediated by double-stranded RNA. A catalytically deficient, histidine-tagged mutant PKR protein [His-PKR(K296R)] was used as the substrate for characterization of the intermolecular phosphoryl...

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Detaylı Bibliyografya
Asıl Yazarlar: Thomis, D C, Samuel, C E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC189345/
https://ncbi.nlm.nih.gov/pubmed/7541849
Etiketler: Etiketle
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