Modulation of Ubc4p/Ubc5p-Mediated Stress Responses by the RING-Finger-Dependent Ubiquitin-Protein Ligase Not4p in Saccharomyces cerevisiae

The Ccr4-Not complex consists of nine subunits and acts as a regulator of mRNA biogenesis in Saccharomyces cerevisiae. The human ortholog of yeast NOT4, CNOT4, displays UbcH5B-dependent ubiquitin-protein ligase (E3 ligase) activity in a reconstituted in vitro system. However, an in vivo role for thi...

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Autori principali: Mulder, Klaas W., Inagaki, Akiko, Cameroni, Elisabetta, Mousson, Florence, Winkler, G. Sebastiaan, De Virgilio, Claudio, Collart, Martine A., Timmers, H. Th. Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright © 2007 by the Genetics Society of America 2007
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1893070/
https://ncbi.nlm.nih.gov/pubmed/17513889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.060640
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