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Survival Quantitative Trait Locus Fine Mapping by Measuring and Testing for Hardy–Weinberg and Linkage Disequilibrium

I show that fine-scale localization of a survival-related locus can be accomplished on the basis of deviations from Hardy–Weinberg equilibrium and linkage disequilibrium at closely linked marker loci. The method is based on χ(2)-tests and they can be performed for age-specific samples of alive (or d...

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Detalhes bibliográficos
Autor principal: Casellas, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2007 by the Genetics Society of America 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1893058/
https://ncbi.nlm.nih.gov/pubmed/17409083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.067264
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