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QTL Fine Mapping by Measuring and Testing for Hardy-Weinberg and Linkage Disequilibrium at a Series of Linked Marker Loci in Extreme Samples of Populations

It has recently been demonstrated that fine-scale mapping of a susceptibility locus for a complex disease can be accomplished on the basis of deviations from Hardy-Weinberg (HW) equilibrium at closely linked marker loci among affected individuals. We extend this theory to fine-scale localization of...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Deng, Hong-Wen, Chen, Wei-Min, Recker, Robert R.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society of Human Genetics 2000
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288140/
https://ncbi.nlm.nih.gov/pubmed/10712216
תגים: הוספת תג
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