Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteins.

Herpes simplex virus (HSV) virions contain one or more factors that trigger rapid shutoff of host protein synthesis and accelerated decay of cellular and viral mRNAs in infected cells. HSV isolates bearing mutations at the virion host shutoff (vhs) locus (gene UL41) are defective for both processes,...

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Pubblicato in:	J Virol
Autori principali:	Jones, F E, Smibert, C A, Smiley, J R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4863-4871.1995
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