Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteins.

Herpes simplex virus (HSV) virions contain one or more factors that trigger rapid shutoff of host protein synthesis and accelerated decay of cellular and viral mRNAs in infected cells. HSV isolates bearing mutations at the virion host shutoff (vhs) locus (gene UL41) are defective for both processes,...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Jones, F E, Smibert, C A, Smiley, J R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4863-4871.1995
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