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Dynamic oligomeric conversions of the cytoplasmic RCK domains mediate MthK potassium channel activity
The crystal structure of the RCK-containing MthK provides a molecular framework for understanding the ligand gating mechanisms of K(+) channels. Here we examined the macroscopic currents of MthK in enlarged Escherichia coli membrane by patch clamp and rapid perfusion techniques and showed that the c...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892972/ https://ncbi.nlm.nih.gov/pubmed/17287352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609085104 |
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