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Plasticity of genetic interactions in metabolic networks of yeast

Why are most genes dispensable? The impact of gene deletions may depend on the environment (plasticity), the presence of compensatory mechanisms (mutational robustness), or both. Here, we analyze the interaction between these two forces by exploring the condition-dependence of synthetic genetic inte...

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Detalhes bibliográficos
Main Authors: Harrison, Richard, Papp, Balázs, Pál, Csaba, Oliver, Stephen G., Delneri, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892960/
https://ncbi.nlm.nih.gov/pubmed/17284612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607153104
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