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Interleukin 7 reduces the levels of spontaneous apoptosis in CD4(+) and CD8(+) T cells from HIV-1-infected individuals

Apoptosis has been suggested as one of the major mechanisms of CD4(+) T cell depletion during the course of HIV type 1 (HIV-1) infection. Here, we show that interleukin 7 (IL-7), a nonredundant cytokine that plays essential roles in the generation and homeostasis of the T cell compartment of the imm...

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Hlavní autoři: Vassena, Lia, Proschan, Michael, Fauci, Anthony S., Lusso, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892954/
https://ncbi.nlm.nih.gov/pubmed/17284597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610775104
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