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Internal strain regulates the nucleotide binding site of the kinesin leading head

In the presence of ATP, kinesin proceeds along the protofilament of microtubule by alternated binding of two motor domains on the tubulin binding sites. Because the processivity of kinesin is much higher than other motor proteins, it has been speculated that there exists a mechanism for allosteric r...

詳細記述

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書誌詳細
主要な著者: Hyeon, Changbong, Onuchic, José N.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892953/
https://ncbi.nlm.nih.gov/pubmed/17287347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610939104
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