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Internal strain regulates the nucleotide binding site of the kinesin leading head

In the presence of ATP, kinesin proceeds along the protofilament of microtubule by alternated binding of two motor domains on the tubulin binding sites. Because the processivity of kinesin is much higher than other motor proteins, it has been speculated that there exists a mechanism for allosteric r...

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Detalhes bibliográficos
Main Authors: Hyeon, Changbong, Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892953/
https://ncbi.nlm.nih.gov/pubmed/17287347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610939104
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