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Internal strain regulates the nucleotide binding site of the kinesin leading head

In the presence of ATP, kinesin proceeds along the protofilament of microtubule by alternated binding of two motor domains on the tubulin binding sites. Because the processivity of kinesin is much higher than other motor proteins, it has been speculated that there exists a mechanism for allosteric r...

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Bibliografske podrobnosti
Main Authors: Hyeon, Changbong, Onuchic, José N.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892953/
https://ncbi.nlm.nih.gov/pubmed/17287347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610939104
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