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1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCδ enzymatic activities

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration has been used, in various mammalian species, as an experimental model of Parkinson's disease. The pathogenesis for such pharmacologically induced Parkinson's disease involves 1-methyl-4-phenylpyridinium (MPP+), the active metaboli...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Serulle, Yafell, Morfini, Gerardo, Pigino, Gustavo, Moreira, Jorge E., Sugimori, Mutsuyuki, Brady, Scott T., Llinás, Rodolfo R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892934/
https://ncbi.nlm.nih.gov/pubmed/17287339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611227104
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