Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors.

Alpha/beta interferon (IFN) and gamma IFN exert widely overlapping biological effects. Still, mice with individually inactivated alpha/beta or gamma receptors exhibit variably severely reduced resistance to infection and altered immune responses. To investigate to what extent the two IFN systems are...

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Main Authors: van den Broek, M F, Müller, U, Huang, S, Aguet, M, Zinkernagel, R M
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC189290/
https://ncbi.nlm.nih.gov/pubmed/7609046
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