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Altered Regulation Of β-Like Globin Genes By A Redesigned Erythroid Transcription Factor

OBJECTIVE: Targeted regulation of β-like globin genes was studied using designer zinc finger transcription factors containing the DNA binding domain of the red cell specific transcription factor EKLF fused to repression domains. METHODS: Globin gene expression was analyzed after introduction of the...

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Hlavní autoři: Manwani, Deepa, Galdass, Mariann, Bieker, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892846/
https://ncbi.nlm.nih.gov/pubmed/17198872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2006.09.004
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