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TNF-Alpha Knockout and Minocycline Treatment Attenuates Blood Brain Barrier Leakage in MPTP-Treated Mice

Following intraparenchymal injection of the dopamine (DA) neurotoxin 6-hydroxydopamine, we previously demonstrated passage of fluoresceinisothiocyanate labeled albumin (FITC-LA) from blood into the substantia nigra (SN) and striatum suggesting damage to the blood-brain barrier (BBB). The factors con...

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Détails bibliographiques
Auteurs principaux: Zhao, Chaohui, Ling, Zaodung, Newman, Mary B., Bhatia, Ankush, Carvey, Paul M.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892817/
https://ncbi.nlm.nih.gov/pubmed/17234424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.11.012
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