Impaired Cognitive Flexibility and Motor Inhibition in Unaffected First-Degree Relatives of Patients with Obsessive-Compulsive Disorder

OBJECTIVE: Obsessive-compulsive disorder (OCD) is highly heritable. Attempts to delineate precise genetic contributions have met with limited success. There is an ongoing search for intermediate cognitive brain markers (endophenotypes) that may help clarify genetic contributions. The aim was to asse...

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Bibliographic Details
Main Authors: Chamberlain, Samuel R., Fineberg, Naomi A., Menzies, Lara A., Blackwell, Andrew D., Bullmore, Edward T., Robbins, Trevor W., Sahakian, Barbara J.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892796/
https://ncbi.nlm.nih.gov/pubmed/17267798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.164.2.335
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