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Novel roles of the IGF-IGFBP axis in etiopathophysiology of diabetic nephropathy
Mechanisms contributing to development of diabetic nephropathy (DN) remain unclear. High ambient glucose level transforms intracellular pathways, promoting stable phenotypic changes in the glomerulus such as mesangial cell hypertrophy, podocyte apoptosis, and matrix expansion. Insulin-like growth fa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892792/ https://ncbi.nlm.nih.gov/pubmed/17011663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diabres.2006.09.012 |
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