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Novel actions of IGFBP-3 on intracellular signaling pathways of insulin-secreting cells

Understanding mechanisms underlying apoptotic destruction of insulin-secreting cells is critical to validate therapeutic targets for type 1 diabetes mellitus. We recently reported insulin-like growth factor binding protein-3 (IGFBP-3) as a novel mediator of apoptosis in insulin-secreting cells. In l...

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Detalhes bibliográficos
Main Authors: Chen, Xiaoyan, Ferry, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092594/
https://ncbi.nlm.nih.gov/pubmed/16275148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2005.09.003
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