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Exclusion of germ plasm proteins from somatic lineages by cullin-dependent degradation

In many animals, establishment of the germ line depends on segregation of a specialized cytoplasm, or ‘germ plasm’, to a small number of germline precursor cells during early embryogenesis1. Germ plasm asymmetry involves targeting of RNAs and proteins to a specific region of the oocyte and/or embryo...

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Autori principali: DeRenzo, Cynthia, Reese, Kimberly J., Seydoux, Geraldine
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892537/
https://ncbi.nlm.nih.gov/pubmed/12894212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature01887.
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