Chromosomal Enrichment and Activation of the Aurora B Pathway Are Coupled to Spatially Regulate Spindle Assembly

Chromatin-induced spindle assembly depends on regulation of microtubule depolymerizing proteins by the chromosomal passenger complex (CPC), consisting of Incenp, Survivin, Dasra (Borealin) and the kinase Aurora B, but the mechanism and significance of the spatial regulation of Aurora B activity rema...

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Main Authors: Kelly, Alexander E., Sampath, Srinath C., Maniar, Tapan A., Woo, Eileen M., Chait, Brian T., Funabiki, Hironori
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892535/
https://ncbi.nlm.nih.gov/pubmed/17199039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2006.11.001
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https://ncbi.nlm.nih.gov/pmc/articles/PMC1892535/
https://ncbi.nlm.nih.gov/pubmed/17199039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2006.11.001