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Association of E6AP (UBE3A) with Human Papillomavirus Type 11 E6 Protein
The cellular E3 ubiquitin ligase E6AP (UBE3A) interacts with the cancer associated HPV E6 oncoproteins, where together with the viral E6 oncoprotein it binds and targets the degradation of the p53 tumor suppressor. We find that the HPV-11 E6 protein also associates with E6AP in vivo, and thereby can...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892534/ https://ncbi.nlm.nih.gov/pubmed/17023019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.08.038 |
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