Introduction of Estrogen Receptor-α into the tTA/TAg Conditional Mouse Model Precipitates the Development of Estrogen-Responsive Mammary Adenocarcinoma

Conditional expression of estrogen receptor (ER)-α) was introduced into tetracycline-responsive MMTV-tTA/tetop-TAg mice to develop a mouse model of estrogen-responsive ER-α-positive mammary adenocarcinoma. Mammary adenocarcinomas developed in the mice with a mean latency of 11 months. Precursor lesi...

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Hlavní autoři: Tilli, Maddalena T., Frech, M. Silvina, Steed, Mary E., Hruska, Kathleen S., Johnson, Michael D., Flaws, Jodi A., Furth, Priscilla A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2003
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892450/
https://ncbi.nlm.nih.gov/pubmed/14578170
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