Introduction of Estrogen Receptor-α into the tTA/TAg Conditional Mouse Model Precipitates the Development of Estrogen-Responsive Mammary Adenocarcinoma

Conditional expression of estrogen receptor (ER)-α) was introduced into tetracycline-responsive MMTV-tTA/tetop-TAg mice to develop a mouse model of estrogen-responsive ER-α-positive mammary adenocarcinoma. Mammary adenocarcinomas developed in the mice with a mean latency of 11 months. Precursor lesi...

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Bibliografiske detaljer
Main Authors: Tilli, Maddalena T., Frech, M. Silvina, Steed, Mary E., Hruska, Kathleen S., Johnson, Michael D., Flaws, Jodi A., Furth, Priscilla A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2003
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892450/
https://ncbi.nlm.nih.gov/pubmed/14578170
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