Human SPF45, a Splicing Factor, Has Limited Expression in Normal Tissues, Is Overexpressed in Many Tumors, and Can Confer a Multidrug-Resistant Phenotype to Cells

Our effort to identify novel drug-resistant genes in cyclophosphamide-resistant EMT6 mouse mammary tumors led us to the identification of SPF45. Simultaneously, other groups identified SPF45 as a component of the spliceosome that is involved in alternative splicing. We isolated the human homologue a...

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Detalhes bibliográficos
Principais autores: Sampath, Janardhan, Long, Pandy R., Shepard, Robert L., Xia, Xiaoling, Devanarayan, Viswanath, Sandusky, George E., Perry, William L., Dantzig, Anne H., Williamson, Mark, Rolfe, Mark, Moore, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892446/
https://ncbi.nlm.nih.gov/pubmed/14578179
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